To understand how indigestion happens and how antacids help relieve it, let’s explore the science behind digestion, the role of stomach acid, and the neutralizing action of antacids in a student-friendly way.
What Is Indigestion?
Indigestion, also known as dyspepsia, can be defined as difficulty in digesting food, leading to discomfort or pain in the upper abdomen. It often feels like a burning sensation, bloating, nausea, or an uneasy feeling after eating.
Indigestion is not a disease in itself but a symptom of digestive imbalance. It can occur due to excessive acid in the stomach, overeating, or irritation caused by spicy or fatty foods.
Simple definition:
Indigestion is a condition where the stomach has trouble processing food efficiently, causing discomfort and pain in the digestive tract.
The Role of Stomach Acid in Digestion
Our stomach produces hydrochloric acid (HCl), a strong acid that plays a vital role in digestion. It creates an acidic environment that allows the enzyme pepsin to break down proteins from food into smaller, absorbable components.
However, when the stomach secretes too much acid, it leads to acid irritation of the stomach lining, resulting in indigestion or heartburn.
Normal Function of HCl
- Activates digestive enzyme pepsin.
- Helps kill harmful bacteria ingested with food.
- Maintains an acidic pH necessary for digestion.
When Problems Occur
- Excess HCl secretion → acid reflux or heartburn.
- Irritation of the stomach or esophageal lining → burning pain and discomfort.
- Delay in emptying stomach contents → bloating and nausea.
Symptoms of Indigestion
Indigestion can present in several ways, depending on its cause. The most common symptoms include:
- Burning sensation in the upper abdomen or chest (heartburn)
- Bloating or fullness after meals
- Belching or gas
- Nausea or vomiting
- Sour taste in the mouth due to acid reflux
- Discomfort or pain behind the breastbone
Note: These symptoms are often worse after eating large meals, eating too fast, lying down soon after meals, or consuming caffeine and spicy foods.
Common Causes of Indigestion
There are multiple factors that can lead to indigestion, both lifestyle-related and medical.
| Category | Causes |
|---|---|
| Dietary | Overeating, spicy or fatty food, alcohol, caffeine, carbonated drinks |
| Lifestyle | Eating too quickly, lying down after meals, stress |
| Medical | Acid reflux (GERD), gastritis, stomach ulcers |
| Medications | Painkillers (NSAIDs), antibiotics, iron supplements |
| Others | Smoking, irregular eating patterns, anxiety |
In short: Indigestion often results from an imbalance between stomach acid production and the body’s ability to neutralize it.
Understanding Heartburn and Acid Reflux
Heartburn is a burning pain in the chest caused by acid reflux, a condition in which stomach acid flows backward into the esophagus (food pipe).
This happens because the lower esophageal sphincter (LES)—a muscle at the end of the esophagus—fails to close properly. As a result, acid from the stomach irritates the esophageal lining, causing that characteristic burning sensation.
Key Points:
- Heartburn is a symptom of acid reflux.
- It often feels like a burning sensation behind the breastbone.
- It may worsen when lying down or bending over.
Antacids are among the oldest and most effective remedies for heartburn and acid reflux.
How Antacids Work
When the stomach produces excess acid, antacids come to the rescue.
Antacids are mild alkaline substances that neutralize the excess acid in the stomach, providing quick relief from acidity and indigestion.
Chemical Reaction:
This neutralization reaction reduces acidity and soothes irritation of the stomach lining.
Example:
When magnesium hydroxide reacts with hydrochloric acid, it forms magnesium chloride and water—relieving acid discomfort.
Common Types of Antacids
There are several types of antacids available, each with different ingredients, strengths, and side effects. Let’s look at the most commonly used ones.
| Antacid | Formula | Neutralizing Power | Unwanted Effects |
|---|---|---|---|
| Sodium Bicarbonate | NaHCO₃ | Low | Fluid retention, alkalosis |
| Magnesium Hydroxide | Mg(OH)₂ | High | Diarrhea, magnesium toxicity |
| Aluminum Hydroxide | Al(OH)₃ | Modest | Constipation, phosphate binding |
| Calcium Carbonate | CaCO₃ | Very High | Acid rebound (increased acid after effect) |
Explanation of Each:
1. Sodium Bicarbonate (Baking Soda):
A common household antacid that provides quick relief. However, it has a short-lasting effect and may cause gas or fluid retention.
2. Magnesium Hydroxide (Milk of Magnesia):
A mild base that neutralizes stomach acid effectively. It also acts as a laxative, so overuse may cause diarrhea.
3. Aluminum Hydroxide:
Neutralizes acid moderately and is often combined with magnesium hydroxide to balance bowel effects. It can cause constipation if taken excessively.
4. Calcium Carbonate (Chalk):
Very effective but can cause an "acid rebound"—increased acid production after the effect wears off. It’s still a popular ingredient in chewable tablets.
Combination Antacids
Most modern antacids are combinations of different active ingredients to balance their effects.
For example:
- Aluminium hydroxide + Magnesium hydroxide: Reduces acid without causing constipation or diarrhea.
- Sodium bicarbonate + Citric acid: Used in effervescent tablets for quick relief.
Some antacids also include alginates—substances that form a foamy layer on top of stomach contents to prevent acid reflux into the esophagus. These are especially useful for heartburn and acid regurgitation.
Forms of Antacids
Antacids are available in different forms to suit patient preference and need.
| Form | Features | Example |
|---|---|---|
| Liquid Antacid | Fast-acting, easy to absorb | Milk of Magnesia |
| Tablet Antacid | Convenient, portable | Tums, Digene tablets |
| Effervescent Tablets | Dissolve in water for quick action | ENO, Gelusil sachet |
| Combination Antacids | Blend of multiple bases | Aluminium + Magnesium hydroxide |
Note: Liquid antacids generally act faster and have higher neutralizing power, while tablets are slower but more convenient.
Unwanted Effects of Antacids
Although antacids are safe for short-term use, overuse can lead to side effects depending on their composition.
| Antacid Type | Possible Side Effects |
|---|---|
| Sodium Bicarbonate | Gas formation, alkalosis, fluid retention |
| Magnesium Hydroxide | Diarrhea, electrolyte imbalance |
| Aluminum Hydroxide | Constipation, reduced phosphate absorption |
| Calcium Carbonate | Rebound acidity, kidney stones (if overused) |
Always follow the prescribed dosage and avoid long-term unsupervised use, as excessive neutralization can interfere with normal digestion.
Why Antacids Are Effective
Antacids offer relief because they work directly on the cause—excess acid. They:
- Neutralize stomach acid instantly.
- Reduce irritation of the stomach and esophagus.
- Help restore normal pH levels in the digestive tract.
- Provide quick relief from pain and discomfort.
However, they only provide temporary relief. For chronic acidity or repeated indigestion, doctors may recommend proton pump inhibitors (PPIs) or H₂ blockers that reduce acid production at the source.
Preventing Indigestion – Healthy Habits
While antacids are effective for short-term relief, prevention is the best approach. Adopting healthy eating and lifestyle habits can significantly reduce indigestion episodes.
| Do’s | Don’ts |
|---|---|
| Eat slowly and chew food well | Avoid overeating |
| Eat smaller, frequent meals | Avoid lying down immediately after eating |
| Drink plenty of water | Limit caffeine and alcohol |
| Include fiber-rich foods | Avoid smoking |
| Manage stress through yoga or meditation | Avoid spicy and oily foods |
Real-Life Applications
- Medical Use: Antacids are prescribed for acidity, gastritis, peptic ulcers, and reflux disease.
- Everyday Use: Baking soda (NaHCO₃) is a common home remedy for mild acidity.
- Food Industry: Calcium carbonate is used as a food additive and acidity regulator.
These examples show how chemistry connects with daily life through simple yet effective compounds like antacids.
| Concept | Explanation | Example/Remedy |
|---|---|---|
| Cause of Indigestion | Excess stomach acid | Acid reflux, overeating |
| Role of HCl | Aids digestion, activates pepsin | Hydrochloric acid |
| Relief Mechanism | Neutralization of acid | Antacids |
| Common Antacids | Mg(OH)₂, NaHCO₃, CaCO₃ | Milk of Magnesia, Baking Soda |
| Prevention | Balanced diet, stress control | Avoid spicy/fatty food |
FAQ
Q1. What causes indigestion?
Indigestion is mainly caused by excess stomach acid, overeating, spicy food, stress, or acid reflux.
Q2. What is the function of hydrochloric acid in the stomach?
It helps in digestion by activating enzymes and killing harmful microbes. However, excess acid causes irritation.
Q3. How do antacids work?
Antacids are basic compounds that neutralize excess acid in the stomach, relieving pain and discomfort.
Q4. Which antacid has the highest neutralizing power?
Calcium carbonate (CaCO₃) has the highest neutralizing power but may cause acid rebound.
Q5. Can we use baking soda for acidity?
Yes, sodium bicarbonate (baking soda) can provide quick relief, but frequent use is not advised due to side effects.
Q6. Why are liquid antacids more effective than tablets?
Liquids act faster as they spread evenly and start neutralizing acid immediately, whereas tablets take time to dissolve.
Q7. What is the difference between magnesium hydroxide and aluminum hydroxide?
Magnesium hydroxide may cause diarrhea, while aluminum hydroxide may cause constipation; hence they are often combined.

