Respiratory Medications - Asthma, COPD, and Beyond

Ruhi Singh
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Respiratory medications are essential for individuals with conditions like asthma and chronic obstructive pulmonary disease (COPD). These medications help manage symptoms and improve breathing. Let's delve into the two primary types of respiratory medications:

1. Beta-2 Agonists (Suffix: -terol)

Action: Beta-2 agonists relax the muscles in the airways, leading to bronchodilation and improved airflow.

Types:

Short-Acting Beta-2 Agonists (SABAs): Used for acute asthma attacks. Examples include albuterol and levalbuterol.

Long-Acting Beta-2 Agonists (LABAs): Used for long-term prevention of asthma symptoms. Examples include salmeterol and formoterol.

Side Effects: Tachycardia, jittery, nervous, palpitations, tremor.

Key: If used in combination with a corticosteroid or anticholinergic, give the beta-2 agonist first.

Respiratory Medications - Asthma, COPD, and Beyond

2. Corticosteroids (Suffix: -sone, -ide)

Used For: Asthma, rhinitis, autoimmune disorders.

Action: Reduce inflammation in the airways by suppressing the immune system.

Types:

Inhaled Corticosteroids (ICS): Used for long-term asthma control. Examples include beclomethasone, fluticasone, and budesonide.

Oral Corticosteroids: Used for severe asthma exacerbations or other inflammatory conditions. Examples include prednisone and methylprednisolone.

Side Effects: Osteoporosis, increased glucose and potassium levels, fluid retention, peptic ulcer disease, immunosuppression.

May Cause: Headache, sore throat, hoarseness, candidiasis (oral thrush).

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Remember:

- Stress may increase the need for higher doses.

- Never stop taking corticosteroids abruptly; taper off gradually.

- Monitor vital signs for signs of infection.

- Avoid NSAIDs.

- Use a spacer and rinse your mouth after using inhaled corticosteroids to prevent oral thrush.

Types of Respiratory Medications

Types of Respiratory Medications

1. Expectorants:

Purpose: Used for non-productive coughs to loosen mucus and make it easier to cough up.

Action: Decrease the viscosity of lung secretions, making the cough more productive.

Example: Guaifenesin

Side Effects: Headache, dizziness, nausea, vomiting.

Important Note: Prolonged use may mask an underlying serious condition for which you have the cough.

2. Mucolytics:

Purpose: Used for pulmonary disorders with thick mucus, such as cystic fibrosis (CF), chronic obstructive pulmonary disease (COPD), and pneumonia (PNA).

Action: Breaks down the tenacity and viscosity of secretions.

Example: Acetylcysteine, Dornase alfa

Side Effects: Bronchospasm (watch with asthma), nausea, vomiting, rash.

Important Note: Watch patients with peptic ulcer disease (PUD), asthma, and esophageal varices.

3. Decongestants (Oral and Topical):

Purpose: Used for rhinitis, sinusitis, and the common cold.

Action: Vasoconstricts the respiratory mucosa, reducing inflammation and relieving pain and congestion.

Examples: Phenylephrine, Pseudoephedrine

Side Effects: Palpitations, restlessness, weakness, hypertension, nervousness, rebound congestion.

Important Note: Watch for interactions if taking with other over-the-counter (OTC) products.

4. Antihistamines:

Purpose: Used for seasonal allergies, urticaria, angioedema, and allergic conjunctivitis.

Action: Blocks histamine at histamine-1 receptors, reducing allergy symptoms.

Examples:

- First Generation: Diphenhydramine

- Second Generation: Loratadine, Cetirizine

Side Effects: Itching, sneezing, hives, GI upset, nausea, dry mouth, constipation, sedation, drowsiness, fall risk.

Important Note: Contraindicated in pregnancy.

5. Non-Steroidal Anti-Allergy Cromolyn:

Purpose: Third-line drug for mastocytosis.

Action: Stops mast cells from secreting histamine.

Side Effects: Burning in the nose, itchy and watery eyes, bad taste in the mouth.

Important Note: Not quick-acting; long-term use is required.

6. Subcutaneous Anti-Inflammatory Omalizumab:

Purpose: Used for allergic asthma, chronic idiopathic urticaria.

Action: Blocks the role of IgE, reducing allergic responses.

Side Effects: Itching, mild rash, nausea, dizziness, ear pain, pain in arms or legs.

Important Note: No live vaccines during or after immunosuppressants.

Important Considerations for Respiratory Medications:

  • Always consult your doctor before starting any new medication.
  • Follow the prescribed dosage and instructions carefully.
  • Be aware of potential side effects and interactions with other medications.
  • Store medications properly to maintain their effectiveness.
  • Do not stop taking medication without consulting your doctor.

FAQs

Q: Can I use a beta-2 agonist without a corticosteroid?

A: While SABAs can be used alone for acute asthma attacks, LABAs should always be combined with a corticosteroid for long-term control to prevent side effects.

Q: Are there any risks associated with long-term corticosteroid use?

A: Long-term use of oral corticosteroids can lead to serious side effects like osteoporosis, high blood pressure, and increased risk of infection. Inhaled corticosteroids, when used as prescribed, have fewer side effects.

Q: How often should I use my inhaler?

A: The frequency of inhaler use depends on your individual condition and treatment plan. Follow your doctor's instructions carefully.

Q: What if my inhaler doesn't seem to be working?

A: If your inhaler isn't providing relief, consult your doctor. They may need to adjust your medication or treatment plan.


Note: This information is for general knowledge and educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

See also ..


Cardiovascular Medications

Diuretics

Respiratory Medications

Inhaled Anticholinergics

Hyperlipidemia Medication

Insulin

Anticonvulsant Medication

Antipsychotic Medication

Mood Stabilizers

Anti-Anxiety Medications

Antidepressants

Antiparkinsonian Medications

Muscle Relaxants

ADHD Medication

Alcohol Addiction Treatment

NSAIDs and Acetaminophen

Antibiotics

Antiviral Medications

Opioid Pain Medication

Tuberculosis Medications

Chemotherapy Medications

Trauma Medications

Fluid Therapy

Common Medication Antidotes

Diabetes

Bronchodilators for Asthma and COPD